#27951
Eroding protections for unborn babies in Mexico prompted massive pro-life protests across the country earlier this month as its citizens call for an end to abortion and respect for all life. The Catholic News Agency reports about 200,000 pro-lifers participated in the March for Life in Mexico City alone, and hundreds of thousands more joined marches […]
#27952
George Clooney is worried about Donald Trump running to be America's commander-in-chief again in 2024.
#27953
Republican J.D. Vance slammed the Democrats, including Tim Ryan, for causing attacks on his biracial children when they attempted to link him to the great replacement theory.
#27954
The recently identified, globally predominant SARS-CoV-2 Omicron variant (BA.1) is highly transmissible, even in fully vaccinated individuals, and causes attenuated disease compared with other major viral variants recognized to date[1][1]–[7][2]. The Omicron spike (S) protein, with an unusually large number of mutations, is considered the major driver of these phenotypes[3][3],[8][4]. We generated chimeric recombinant SARS-CoV-2 encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate and compared this virus with the naturally circulating Omicron variant. The Omicron S-bearing virus robustly escapes vaccine-induced humoral immunity, mainly due to mutations in the receptor-binding motif (RBM), yet unlike naturally occurring Omicron, efficiently replicates in cell lines and primary-like distal lung cells. In K18-hACE2 mice, while Omicron causes mild, non-fatal infection, the Omicron S-carrying virus inflicts severe disease with a mortality rate of 80%. This indicates that while the vaccine escape of Omicron is defined by mutations in S, major determinants of viral pathogenicity reside outside of S.
### Competing Interest Statement
The authors have declared no competing interest.
[1]: #ref-1
[2]: #ref-7
[3]: #ref-3
[4]: #ref-8
#27955
There is essentially no chance of escaping a serious economic downturn, according to Bloomberg Economics. | Economy
#27956
Former climate activist Tom Harris discusses how he was once a climate alarmist but now sees it as a scam.
#27957
The Iowa Republican’s explosive allegations, made in a letter sent to Biden administration officials last week, warrant a proper, unbiased investigation.
#27958
Actor and former WWE superstar Dwayne "The Rock" Johnson previously said he was interested in running for president, but now says he is too focused on family for the job.
#27959
The following is an adapted excerpt from the contribution by the late Angelo M. Codevilla to Against the Great Reset: Eighteen Theses Contra the New World Order, which will be released by Bombardier Books on Oct. 18. The book is a collection of original essays from eminent thinkers, writers, and…
#27960
A Hong Kong protester was dragged onto the grounds of the Chinese consulate in Manchester and beaten by ...
#27961
Upstate Rep. Elise Stefanik, the No. 3 House Republican, has said GOP lawmakers could move to impeach President Biden next year after investigating his family’s foreign consulting businesses.
#27962
Deviate from orthodoxy, and you’ll be crushed by the Remainer, ‘expert’-driven establishment
#27963
Chinese dictator Xi Jinping forecast his government's plans to further expand Marxist tyranny throughout China and the world.
#27964
LaRose rolled out an initiative aimed at organizing state and local power to keep bad actors from damaging the election process.
#27965
If this is their closing message, it's a bad one.
#27966
SOLDOTNA, Alaska (AP) — A Satanic Temple member who won the right to open a regional Alaska government meeting declared "Hail Satan" during her first invocation, prompting about a dozen officials and attendees to walk out...
#27967
MSNBC legal analyst Andrew Weissmann claimed during a Monday MSNBC appearance that the FBI was “all over” Black Lives Matter protests in 2020, but was
#27968
Biden admin pressured Dem El Paso mayor not to declare state of emergency over city’s migrant crisis
“It is a sleight of hand what the administration is doing — pressuring the local government to not issue a declaration of emergency, to say as if everything is going OK.”
#27969
The S&P 500 is down more than 5% since President Joe Biden’s inauguration and the Dow Jones industrials more than 4%.
#27970
During a recent visit to an ice cream shop, President Joe Biden lit into British prime minister Liz Truss and her tax proposals
#27971
Every morning 100 senators wake up, look in the mirror, and see a future president looking back at them.
#27972
His interview with NBC News’ Dasha Burns last week revealed the extent of auditory processing issues that have lingered since the 53-year-old’s stroke in May.
#27973
Gisele Baretto Fetterman demanded an apology for MSNBC’s “ableist” comments toward husband and U.S. Senate candidate John Fetterman, the Independent reported on Monday. In an exclusive interview with the outlet Gisele accused MSNBC reporter Dasha Burns — who noted the Democratic candidate required the assistance of closed captioning (CC) software to participate — of being ableist. The Senate hopeful […]
#27974
When you have an income tax, you also get massive, snowballing debt.
#27975
President Joe Biden told a reporter in Los Angeles that gas in California has always been $7 a gallon and that gas nationwide is down over $1 dollar.
